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There was some evidence of publication bias (Egger test, P = 0.94), but the trim-and-fill method indicated that this publication bias did not impact the estimate

During that same call, Eli Lilly said it expected sales of Trulicity and some other drugs it makes to level off, saying Flat or eroding contributions from later lifecycle products including Taltz, Trulicity, and Verzenio. Eli Lilly faces dozens of lawsuits filed by patients who say they took Trulicity and suffered from complications like ileus, gastroparesis, and pancreatitis

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Many need a balance of all three

2018 , 155 , 16611669.e4